Tadalafil (Generic Cialis)

Buy Tadalafil Online To Effectively Treat Erectile Dysfunction

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Tadalafil is the active ingredient in Cialis and is now available in its generic form since mid-November 2017.

What is Tadalafil?

Tadalafil is the generic, unbranded version of Cialis, and both are treatments for erectile dysfunction in adult men. Cialis and Tadalafil contain the active ingredient tadalafil and so are medically equivalent. In comparison with other erectile dysfunction treatments, tadalafil has a longer lasting effect.

What is the difference between Tadalafil and Cialis?

Generic medications have the same active ingredient as their branded versions but available on the market at a lower price. Manufacturers of generic medicines have to show that the medicines are equally effective, that is, they have the same strength, quality, stability and efficacy.

What is Tadalafil Daily?

Tadalafil comes in two different forms: tadalafil 36-hour and tadalafil daily. While the former can be taken at least half an hour prior to planned sexual activity, tadalafil daily tablets are taken everyday to give you the option to always be ready for sexual intercourse. Since tadalafil daily is taken everyday, it comes at lower strengths of 2.5mg and 5mg. Tadalafil 36 hour comes in 10mg tablets and 20mg tablets.

What dose should I take?

Depending on your lifestyle and preference, it is up to you whether you take tadalafil 36 hour or tadalafil daily. However, if you have not tried the treatment before, it is recommended that you try the lower dose first and see how you react and if you have any side effects. If you find that the medicine is not sufficient, or not having the desired effect, discuss the options with your GP or local pharmacist, who will be able to either recommend a higher strength, or a more suitable treatment for you.

How does it work?

Tadalafil belongs to a group of medications called phosphodiesterase type 5 inhibitors (PDE5), which relaxes the blood vessels in the penis and allows the blood to flow. Combined with sexual stimulation, tadalafil helps to achieve and maintain the erectile function.

How do I take it?

Tadalafil 36-hour (10mg, 20mg) - Swallow a single pill with water at least half an hour before you plan to have intercourse. You should start with the lower dose of 10mg and you can increase or decrease the dose as required. Do not take more than one tablet in a day.

Tadalafil daily (2.5mg, 5mg) - Take one tablet with water everyday at roughly the same time of day. Do not take more than one tablet per day. The starting recommended dose for Tadalafil Daily is 5mg, which can be adjusted as required.

Please note that if you are taking either Tadalafil Daily or Cialis Daily, it is NOT recommended that you take any other erectile dysfunction at the same time. This includes Viagra, Sildenafil, Cialis 36-hour, Levitra and Spedra.

How long does it take to work?

Tadalafil is absorbed into the body quickly and so is fast-acting, allowing for sexual intercourse just 20 minutes to one hour after taking a tablet. It also needs sexual stimulation to be effective. The pill can be taken with or without food, but a large meal will slow the action of the medication so it will take longer to work.

With Tadalafil Daily, the low dose of the treatment can take up to 5 days to build up to its full potential but after that time, the effect of the daily treatment is continuous. Therefore, you do not have to wait and you will be ready for action whenever you like.

How long does it last?

A single tablet of tadalafil will stay in your body for 36 hours as the active ingredient has a longer lasting action on the body compared to other erectile dysfunction treatments. Since Tadalafil Daily is taken everyday, the effect remains in the body so you can be ready for sexual activity at any time.

Can I take Tadalafil with other ED medications?

You should not take Tadalafil with any other PDE5 inhibitor unless specifically instructed by your doctor. If you would like to try two or more different ED medications, you can do as long as only 1 tablet of any treatment is taken in a 24 hour period. You can see our specially priced ED Trial Packs here

FAQs (skip)

What is Tadalafil?

Tadalafil is the active ingredient in the branded medication Cialis, a medication used to treat erectile dysfunction. Tadalafil is available as the generic version which is produced by alternative manufacturers at a lower price. Tadalafil comes in four different strengths; 2.5mg, 5mg, 10mg and 20mg.

How long does Tadalafil last?

The effects of Tadalafil can last for up to 36 hours. It takes around 30 minutes for Tadalafil to become active in the body, and will then assist in achieving and maintaining an erection. Tadalafil is also available in a daily dosage, where one tablet is taken at the same time every day, making you ready for intercourse at any time.

How does Tadalafil work?

Tadalafil is a medication known as a PDE5 inhibitor. Normally, PDE5 causes blood vessels in the penis to return to their normal size, ending an erection. Tadalafil works by preventing PDE5 from operating in its normal function, thus extending the time an erection can be maintained.

What is the difference between the strengths of Tadalafil?

The strength of Tadalafil will determine how you should take the medication. The lower strengths of 2.5mg or 5mg are for daily use to give you the option of always being ready for sexual intercourse. The higher strengths of 10mg or 20mg are for ‘when required’ use, and should be taken at least 30 minutes before sexual activity. This dosage is not meant for continuous daily use.

The starting recommended dosage of Tadalafil 36 Hour is 10mg. This dose should be taken on four separate occasions to prove its effectiveness.

The starting recommended dosage of Tadalafil Daily is 5mg. This should be taken at the same time every day to maintain a consistent level in your system.

How much Tadalafil should I take?

Only one tablet of any dose of Cialis(Tadalafil) should be taken at any one time. Tadalafil should not be taken at the same time as any other erectile dysfunction medication.

How to take Tadalafil

Only one tablet of Tadalafil should be taken in any 24 hour period, regardless of the dose. It is generally recommended to take Tadalafil with water so that the tablet is easier to swallow. Taking Tadalafil with food may delay its effectiveness, so it is recommended to allow more than 30 minutes if taken after a meal.

How long does Tadalafil take to work?

Tadalafil can be fully effective in the body after 30 minutes but can take up to 2 hours to work, depending on circumstance. It will remain effective in the body for up to 36 hours, and during this time will help you achieve and maintain an erection. While taking Tadalafil, it is still necessary to be sexually aroused.

What is the difference between Tadalafil and Sildenafil?

Tadalafil (Cialis) and Sildenafil (Viagra) are PDE5 inhibitors. Both Tadalafil and Sildenafil have a similar effect within the body, however, both medications may have a different level of effectiveness for each patient. Tadalafil has an effective time of 36 hours in the body whereas Sildenafil has an effective time of 4 hours.

How effective is Tadalafil?

Tadalafil has been proven to be effective in around 80% of cases. This is similar to the effectiveness of Viagra (Sildenafil) and better than both Levitra (Vardenafil) and Spedra (Avanafil).

How long before sex should you take Tadalafil?

For the ‘when required’ strength, you should take Tadalafil at least 30 minutes before you engage in sexual activity. If you take the daily dosage, it is recommended to take Tadalafil at the same time every day. Tadalafil can remain active in the body for up to 36 hours.

Cialis Daily
Strength 2.5mg
How long it lasts All day
Dosage Take one a day
How fast it works Immediately (Continuous effect)
Active Ingredient Tadalafil
Cialis (Tadalafil)
Strength 10mg
How long it lasts Up to 36 Hours
Dosage One tablet 30 minutes before
How fast it works 15 - 30 minutes
Active Ingredient Tadalafil

Tadalafil Side Effects

Like all medications, Tadalafil has side effects that affect some men that take this medication. These occur for every 1 in 10-100 men. Some common side effects of Tadalafil are: 

  • Headaches
  • Face Flushing
  • Indigestion

Notably, Tadalafil has fewer side effects than other medications used to treat erectile dysfunction. In fact, many men who experience nasal congestion, stomach pain, nausea and diarrhoea with other drugs find that Tadalafil doesn’t give them these symptoms.

 Information Leaflet

Always read the patient information leaflet before commencing treatment.

Important: We advise you to always read the patient information leaflet inside the medication box, as the generic medication may not always entirely match the patient information leaflet listed. Please contact us if you have any questions.

Written and reviewed by our qualified team

GPhC Number: 2088658

Carolina Goncalves

Authored by:

Carolina Goncalves


GPhC Number: 2225869

Rehma Gill

Reviewed by:

Rehma Gill


Find out more about how we ensure the accuracy of our content with our content guidelines.

Content last updated: 01 Nov 2023

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