Zomig

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What is Zomig and how does it work?

Zomig is a treatment for migraines. The class of medications called triptans also known as serotonin 5-HT receptor agonists includes zolmitriptan, the active ingredient in Zomig. It works by constricting the temporarily swollen blood vessels in the head, which is thought to cause migraines. This results in relief from the headache part of a migraine attack.

When and how should I take Zomig?

Zomig is sold as conventional tablets, a nasal spray and dispersible tablets. Swallowing the tablet whole with water as soon as the migraine starts maximises its effect but taking it before the warning signs will not prevent an attack. The recommended dose for Zomig is 2.5mg, and food does not affect the activity of the medication. If your migraine returns, you can take another tablet but only after a minimum of 2 hours has passed since the first dose. Do not take more than 2 tablets per day.

Zomig nasal spray comes in a ready-to-use spray unit which should be administered as soon as your migraine starts. Just a single spray into one nostril is necessary and it will begin to work in around 15 minutes. The dispersible tablet should be placed on the tongue and allowed to dissolve.

How long does it take to work?

The Zomig tablets start to work after about an hour.

How long does it last?

The medication can last approximately 2 hours.

What are the different forms of Zomig available?

There are different forms of Zomig sold. In addition to the conventional Zomig tablets, Zomig Rapimelt dissolves in your mouth, a Zomig nasal spray is available, and you can get a generic version of the drug called Zolmitriptan.

What is the difference between Zomig and Zolmitriptan?

These medicines are medically equivalent and treat migraine headaches in the same way. Although Zomig is a brand name, both Generic Zolmitriptan and Zomig contain zolmitriptan as their active substance. The generic version is cheaper than Zomig.


Only 1 spray into one nostril is required. Zomig nasal spray starts to work in around 15 minutes. The tablets may take between 45 and 60 minutes to work.

What are the side effects of Zomig?

Common side effects of Zomig, which may affect around 1 in 10 people include:

  • Tingling of the fingers and toes
  • Sleepiness
  • Headache
  • Palpitations
  • Nausea
  • Stomach pain
  • Feeling weak
  • Dry mouth

 Information Leaflet

Always read the patient information leaflet before commencing treatment.
  • The patient information leaflet can be found here.

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Read the full article: Migraines: Curious Triggers

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Read the full article: Imigran vs Zomig

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