Mounjaro (Tirzepatide)

Weight Loss Injection

Mounjaro is a weekly injectable medication prescribed for type 2 diabetes management that contains Tirzepatide, and has been reported to assist with weight loss.
Mounjaro (Tirzepatide)
Images for illustrative purposes only

What is Mounjaro?

Mounjaro contains the active ingredient Tirzepatide, a recently approved medication for type 2 diabetes that also demonstrates promising weight loss results, making it a potential option for off-label use in obesity treatment.

As a prescription injectable medication, Mounjaro helps to effectively manage blood sugar levels when used in conjunction with a healthy diet and regular exercise in adults with type 2 diabetes.

Currently, Tirzepatide is only prescribed as a second-line medication for type 2 diabetes, similar to other GLP-1 medications, and administered through a once-a-week subcutaneous injection.

How does Mounjaro work?

Tirzepatide, a synthetic peptide, acts as a dual agonist for gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptors.

By functioning as a dual GIP agonist and GLP-1 agonist, Tirzepatide maximises the comparable advantages observed in GLP-1 medications like semaglutide.

The unique dual agonism of Tirzepatide produces a greater reduction in hyperglycemia compared to GLP-1 agonists alone, while also suppressing appetite.

How does Mounjaro help you lose weight?

Mounjaro aids in weight loss by reducing appetite, helping to reduce food intake and calorie consumption.

It may be prescribed alongside a reduced-calorie diet, increased physical activity, and healthy lifestyle choices to promote long-term weight management.

Here at Pharmica, you can purchase clinically proven, fully licensed alternative weight loss treatments to Mounjaro. For more guidance, read more about how to get the most out of your weight loss medication to achieve consistent weight loss results.

How effective is Mounjaro for weight loss?

According to current clinical data from a study conducted over a 40-week period, it was found that a 5mg dose of tirzepatide resulted in a weight reduction of 5.4 kg, whereas a 15mg dose led to a significant weight loss of 10.5 kg.

This dose-dependent correlation between tirzepatide dosage and weight loss is consistent with the effects observed with semaglutide, a widely used GLP-1 medication for managing weight loss.

What are the side effects of Mounjaro?

As with any medication, individual experiences with side effects may vary, and it is important to discuss potential concerns and side effects with a healthcare provider before starting to take Mounjaro.

Common side effects of Mounjaro include:

  • Allergic reaction (Rash, itching, and eczema)
  • Decreased appetite
  • Stomach Pain
  • Vomiting
  • Indigestion
  • Constipation
  • Stomach bloating
  • Burping
  • Gas
  • Reflux or heartburn
  • Fatigue
  • Injection site reaction (Itching or redness)
  • Fast Pulse
  • Increased level of enzymes in blood

Rarer side effects include:

  • Pancreatitis
  • Hypoglycaemia
  • Gallstones
  • Increased calcitonin levels in blood.

Please review the Patient Information Leaflet before starting the treatment.

Is Mounjaro safe?

While Mounjaro has shown effectiveness in promoting weight loss, it is important to consider the potential side effects and individual health factors when assessing its safety.

Key Considerations for taking Mounjaro:

  • Not to be used if you are allergic to any of the ingredients in Mounjaro, including Tirzepatide. Consult the Patient Information Leaflet for a comprehensive list of ingredients.
  • Not recommended for children or adolescents under 18 years old.
  • Avoid use during pregnancy or breastfeeding.
  • Not suitable for those with a history of pancreatitis.

As with any medication, the safety of Mounjaro should be evaluated on a case-by-case basis, with careful consideration of the individual's medical history and consultation with a healthcare professional.

When will Mounjaro be released in the UK?

The release date of Mounjaro in the UK is subject to regulatory approval and market authorisation.

More evidence on the clinical and cost-effectiveness of this new treatment option for people with type 2 diabetes is needed before it can be recommended for NHS use, as stated by a NICE committee.

Where can I buy Mounjaro in the UK?

Mounjaro is a prescription medication that will be available for purchase through pharmacies and online services once it receives regulatory approval and market authorisation.

However, you can purchase alternative weight loss treatments in the UK that are clinically proven and effective.

Can I get Mounjaro weight loss treatment on the NHS?

Mounjaro is currently undergoing evaluation for potential approval by the NHS as a weight loss treatment.

How much does Mounjaro cost in the UK?

Mounjaro is not currently available for purchase in the UK, the price of this weight loss treatment is still to be determined.

Is Mounjaro the same as Wegovy?

Mounjaro is not the same as Wegovy. While both medications can aid in weight loss, they have different mechanisms of action and specific dosage instructions.

Mounjaro is prescribed to treat type 2 diabetes and contains Tirzepatide, a synthetic peptide that works as a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist.

On the other hand, Wegovy is designed to be prescribed specifically for weight loss, contains semaglutide and belongs to the class of GLP-1 receptor agonists.

Is Mounjaro the same as Ozempic?

Mounjaro is not the same as Ozempic. While both medications can assist with weight loss, they have different mechanisms of action and specific dosage instructions.

Mounjaro, prescribed for type 2 diabetes, contains Tirzepatide, a synthetic peptide that acts as a dual agonist for gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptors.

On the other hand, Ozempic is prescribed for individuals with type 2 diabetes to assist in managing blood glucose levels and contains semaglutide.

While both treatments share the property of promoting weight loss, It's important to consult with a healthcare professional to determine which medication is appropriate for your specific needs.

What are the alternatives to Mounjaro in the UK?

Another effective and medically approved weight loss treatment available in the UK is Orlistat - a weight loss tablet that helps you reduce the absorption of dietary fat in the body.

When combined with a healthy, reduced-calorie diet and regular exercise, Orlistat can support weight loss of up to 50% more than from just dieting.

 Information Leaflet

Always read the patient information leaflet before commencing treatment.

Important: We advise you to always read the patient information leaflet inside the medication box, as the generic medication may not always entirely match the patient information leaflet listed. Please contact us if you have any questions.

Written and reviewed by our qualified team

GPhC Number: 2088658

Carolina Goncalves
Authored by: Carolina Goncalves Superintendent
Pharmacist

GPhC Number: 2225869

Rehma Gill
Reviewed by: Rehma Gill Pharmacy
Manager

Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 10 Aug 2023

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