Differin (Adapalene) 0.1%

Differin (Adapalene) Is A Powerful, Highly Effective Acne Treatment

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Differin (Adapalene) gel and cream are effective acne treatments, clinically proven to clear and prevent mild to moderate acne.

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What is Differin and how does it help to clear my acne?

Differin contains the active ingredient Retinoid Adapalene, which is clinically proven to clear and prevent mild to moderate acne. Adapalene is an anti-inflammatory medicine, highly effective at reducing the formation of whiteheads and blackheads on the outer layer of skin. Differin is non-comedogenic and fragrance-free; it actively helps to prevent breakouts, whiteheads, blackheads, clogged pores and blemishes. Differin is ideal for daily use in either a gel or cream to remove acne and return skin back to its healthy tone and texture.

What are the benefits of Differin (Adapalene) gel and cream?

  • Contains Retinoid Adapalene to actively clear acne.
  • Prevents breakouts, whiteheads, blackheads, clogged pores and blemishes.
  • Restores skin tone and texture.
  • Non-comedogenic.
  • Fragrance-free.

How long does it take to start seeing results while using Differin?

As with all acne medication, results may not be seen before 12 weeks. However, in many cases, results can be observed following continued use during a 12 week period. It is important to use Differin consistently and continually to ensure you get the best results.

How do I use Differin (Adapalene) gel and cream?

Apply a thin layer of Differin cream or gel once a day, all over your face. For practicality, application before bedtime is recommended.

Be careful not to apply Differin to sensitive areas such as the mouth, nostrils or eyes. Take care to wash your hands before and after use. Do not apply Differin to broken skin. Temporary skin irritation (retinization) can occur while adjusting to the active ingredient, this should subside by week 4. Always read the patient information leaflet before use and seek further professional advice if necessary.

 Information Leaflet

Always read the patient information leaflet before commencing treatment.

Written and reviewed by our qualified team

GPhC Number: 2088658

Carolina Goncalves

Authored by:

Carolina Goncalves


GPhC Number: 2225869

Rehma Gill

Reviewed by:

Rehma Gill


Find out more about how we ensure the accuracy of our content with our content guidelines.

Content last updated: 20 Mar 2023

Differin Reviews

9.6/ 10
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Based on 145 independent customer reviews taken by Feefo (see all Feefo Reviews), Google and Trustpilot (see all Trustpilot Reviews).

(read on Feefo)
"Great product and service"

Product Review:

"Great product…will re order"

Service Review:

"Amazing A+"

(read on Feefo)
"Wonderful, reliable and consistently good"

Product Review:

"My face has changed from 'the surface of the moon' to smooth and delightful and the inflammation is much less."

Service Review:

"My Differin is a staple of my skin care. Pharmica are the 'old faithful' friend of excellent product supply, quick turnaround of delivery and always good. Never had any issues and I'm v grateful for the service."

(read on Feefo)

Product Review:

Positive results"

Service Review:

"Excellent product
Easy consultation
Efficient delivery"

(read on Feefo)

Product Review:

"Delighted with the results thus far. Will definitely be reordering."

Service Review:

"Easy to use site, great range of products at excellent prices and very fast delivery. Highly recommended."

(read on Feefo)
"Informative and great to choose correct products"

Product Review:

"Great product for acne it works"

Service Review:

"Easy process"

"Great service"

Product Review:

"It needs careful use as per instructions and works well."

Service Review:

"The website was easy to use, the item arrived quickly and I received email updates."

"Great service"

Product Review:

"Amazing stuff, really cleared my skin with zero irritation. "

Service Review:

"Easy to use website, good prices, good product, great fast service!"

(read on Feefo)
"Great sevice and great fast delivery"

Product Review:

"Good product I use this every night"

Service Review:

"Great service and fast delivery"

"Quick to communicate and dispatch"

Product Review:

"Stick with it, the results are worth it. "

Service Review:

"Quick to communicate and dispatch. Flexible and pragmatic with orders."

"Excellent and great price"

Product Review:

"Fantastic product "

Service Review:

"Excellent and great price"

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