Isotrex Gel (Isotretinoin)

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Isotrex gel is an effective topical anti-acne treatment that unblocks the pores to reduce spots and acne.

What is Isotrex Gel and what is it use for?

It is a topical gel use to treat inflammatory and non-inflammatory acne vulgaris.

What is in it?

The active ingredient in Isotrex gel is isotretinoin, a retinoid similar to Vitamin A used in the topical treatment of acne.

How does it work?

It unblocks the pores and so reduces spots and acne. It loosens blackheads and whiteheads so that they are easily removed and stops new ones being formed.

How do I use it?

Apply a thin layer to the affected skin once to twice daily after gently washing and drying the skin. Remember to wash your hands before and after application. Isotrex should not be used with benzoyl peroxide. If combination treatment is needed, these should be applied during different times of the day. Also, make sure to avoid the mouth, eyes and nostrils as well as any broken skin such as cuts, grazes and especially sunburnt skin.

How long does it take to work?

It can take up to 6-8 weeks before the benefits of Isotrex are visible.

Does it have any side effects?

The treatment could cause skin irritation and tenderness, dry skin, and exfoliation. Upon irritation, treatment should be discontinued. It can also increase sensitivity to sunlight. Please note that using an excess of the medication can increase the chances of experiencing side effects.

Cautions for this medication

  • This product is highly flammable and must be kept well away from any open flames and sources of ignition.
  • Do not use this product if you are pregnant or breastfeeding.
  • Do not use sunbeds during treatment with Isotrex gel.

Do I need a prescription to buy this medication?

Yes, Isotrex Gel is a Prescription Only Medication (POM) and doctor must prescribe the medication before you can purchase it.

What are the side effects of Isotrex Gel?

The treatment could cause skin irritation and tenderness, dry skin, and exfoliation. Upon irritation, treatment should be discontinued. It can also increase sensitivity to sunlight.

 Information Leaflet

Always read the patient information leaflet before commencing treatment.

Written and reviewed by our qualified team

GPhC Number: 2088658

Carolina Goncalves

Authored by:

Carolina Goncalves


GPhC Number: 2225869

Rehma Gill

Reviewed by:

Rehma Gill


Find out more about how we ensure the accuracy of our content with our content guidelines.

Content last updated: 24 Aug 2023

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