Lariam Weekly Tablets Provide Reliable Protection Against Malaria

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Lariam is used to prevent malaria with tablets taken once a week.

Do you need protection against Malaria?

Malarial infection can be life-threatening so if you are entering a malaria prevalent region, it is a good idea to take precautions with anti-malarial tablets. It is also worth noting that each antimalarial is different and while they may be effective against some species of malaria, they might not work for others. Talk to your pharmacist, doctor or travel clinic about your destination, itinerary, the risks and the best course of treatment for your trip.

What is Lariam and what is it used for?

Lariam is an antimalarial medicine used to treat and prevent the development of the malarial parasite P. falciparum in areas with antimalarial drug resistance. It contains the active substance Mefloquine hydrochloride at a dose of 250mg.

How does it work?

When an infected mosquito bites a person, it passes the parasite onto its human target. The choice of antimalarial drug depends on the sensitivity of the malaria parasite in your destination area. Lariam targets the malarial parasite and destroys it.

How do I take Lariam?

Those that have a body weight more than 45kg should take one 250mg tablet once a week on the same day, starting 2 to 3 weeks before entering the malaria-affected area, so you can be sure that you tolerate the medication well before arriving at your destination. Continue the treatment through your stay and 4 weeks after returning. It is recommended that you swallow the tablets whole with plenty of water, preferable after a meal.

How is Lariam different from Malarone?

Although they are both medications used to treat or prevent malarial development in the human body, they have different active ingredients and directions for administration. Also, Lariam has more side effects than Malarone, which are more severe as well.

Contact your doctor if:

If you get any side effects at any time during your treatment, stop taking the treatment immediately and contact your doctor or pharmacist.

Contact your doctor if you experience changes in mood and behaviour, mental problems, or fits. Other signs that you should cease taking Lariam include: suicidal thoughts, severe anxiety, feeling restless, depression, confusion, unusual behaviour, mistrusting others, self-endangering behaviour, and hallucinations.

If you are unsure of treatment with Lariam, you feel that the cautions on the medication apply to you, or if you have had any mental side effects from the medication listed on the patient information leaflet, consult your GP or pharmacist for advice.

Ask your doctor for a replacement antimalarial for as long as you are in the country where malaria is a risk.

What are the side effects of Lariam?

It’s common to experience some side effects with antimalarial medication. Side effects of Lariam may include:

  • stomach pain
  • headache
  • nausea
  • vomiting
  • severe anxiety
  • depression
  • sleeping problems
  • dizziness

Other side effects can include:

  • fits including seizures or convulsions
  • liver problems
  • heart problems
  • diarrhoea
  • vertigo
  • suicidal thoughts
  • confusion
  • unusual behaviour
  • restlessness
  • hallucinations
  • mistrust towards others
  • self-endangering behaviour
  • changes in mood or behaviour

If you experience any of these while on treatment, stop taking Lariam immediately and contact your doctor, who can also provide you with a replacement antimalarial for the period of your stay in a malaria-prevalent region. 

Who should NOT take Lariam?

  • You should not take Lariam if you are pregnant or breastfeeding. If you are considering becoming pregnant you should wait at least 3 months after the last dose.
  • You should not take Lariam if your body weight is 45kg or under.

 Information Leaflet

Always read the patient information leaflet before commencing treatment.

Written and reviewed by our qualified team

GPhC Number: 2088658

Carolina Goncalves

Authored by:

Carolina Goncalves

GPhC Number: 2225869

Rehma Gill

Reviewed by:

Rehma Gill

Find out more about how we ensure the accuracy of our content with our content guidelines.

Content last updated: 15 Jan 2024

Lariam Reviews

9.8/ 10
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Based on 36 independent customer reviews taken by Feefo (see all Feefo Reviews), Google and Trustpilot (see all Trustpilot Reviews).

"Fast service"

Product Review:

"I use these because I only need to use one a week plus my wife has side effects with other ones"

Service Review:

"Fast service Need malaria tablets at short notice as booked a last minute holiday they arrived with in 3 days"

(read on Feefo)

Product Review:

"I have used Larium for over 30 years. Take care if you are a new user"

Service Review:

"Fast and efficient service"

(read on Feefo)

Product Review:

"The service was excellent prompt as expected"

Service Review:

"The service was excellent prompt as expected."

(read on Feefo)

Product Review:

"Not all pharmacies stock these anti malaria drugs so I was very pleased to find a reliable supplier"

Service Review:

"The response from the doctor was quick and the ordering process and delivery time was excellent"

"Excellent service"

Product Review:

"Anti malaria tablet, its seems to be doing the work. "

Service Review:

"Excellent service, highly recommended"

"This was a repeat order"

Product Review:

"I have used this product for a number of years with no side effects. "

Service Review:

"This was a repeat order. Very easy transaction and very prompt delivery."

"Easy ordering and fast shipping"

Product Review:

"Very safe medication "

Service Review:

"Easy ordering and fast shipping"

(read on Feefo)
"Great company, fast delivery and really good service."

Product Review:

"good tablets for prevention of malaria in west africa. Priced very competitively compared to other chemist!"

Service Review:

"Easy to use Website. great selection of products and really competitive prices and super fast delivery too, ideal when your husband is travelling and finds out his malaria tablets are out of date!"

(read on Feefo)
"On time delivery well done!"

Product Review:

"Delivered on time and good"

Service Review:

"Yes I will recommend Pharmica’s service"

"Great with me"

Product Review:

"Good product "

Service Review:

"Good preventative medicine"

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